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Apostle MiniMax 高效游离 DNA 分离试剂盒 (S 版)

特别设计用于DNA 小片段分离 (<100 bp) 


Overview, Apostle MiniMax (Type S)

Powered by Apostle MiniMax technology, Apostle MiniMax High Efficiency cfDNA Isolation Kit (Type S) is an excellent tool for the isolation of ultra-low concentration cell free DNA (cfDNA). Apostle MiniMax High Efficiency cfDNA Isolation Kit (Type S) is featured for its efficient recovery of small DNA fragments ( <100 bp) from biological samples, where major alternative products fail. This feature is quite useful when small DNA molecules have significant presence in the biological sample and need to be isolated.


ProductsCat #Protocol
Apostle MiniMax High Efficiency cfDNA Isolation Kit (Type S) (25-50 preps)
A17830-50
Download Protocol
Apostle MiniMax High Efficiency cfDNA Isolation Kit (Type S) (5-10 preps)
A17830-10
Download Protocol


Performance Data

Compared to major alternative suppliers with magnetic bead technology, Apostle MiniMax High Efficiency cfDNA Isolation Kit (Type S) offers superior DNA isolation efficiency for cfDNA reference spiked in biological medium, especially for cfDNA with size <80 bp (Exhibit 1-3).

Exhibit 1. Superior small DNA isolation efficiency.

A) cfDNA reference standard (Horizon Discovery Ltd, Cat# HD780) was spiked in TE buffer, followed by isolation with Apostle MiniMax High Efficiency cfDNA Isolation Kit (Type S). The isolated DNA was characterized by Bioanalyzer 2100 (red curve), and compared with original cfDNA reference standard (blue curve). Apostle MiniMax High Efficiency cfDNA Isolation Kit (Type S) offers >95% recovery of the cfDNA reference standard, which has significant portion of DNA fragments with size <100 bp.

Exhibit 2. Superior small DNA isolation efficiency.

B) cfDNA reference standard was spiked in TE buffer, followed by isolation with MiniMax Type S and a major alternative product. Bioanalyzer 2100 analysis demonstrated significantly higher cfDNA recovery rate of MiniMax Type S (red curve) compared to a major alternative product (blue curve).

Exhibit 3. Superior small DNA isolation efficiency.

C) Zoom in of B)in the region between 35–100 bp. MiniMax Type S (red curve) is compared to a major alternative product (blue curve). Bioanalyzer 2100 analysis demonstrated the efficient recovery at ~50 bp of MiniMax Type S (red curve), while a major alternative product (blue curve) failed.

Nature 子刊 Nature Communications 近期发表又一项高影响力国际临床研究,其中应用 Apostle 艾铂图 MiniMax 游离核酸技术。此研究包括2125名癌症患者,9种不同的癌症类型。此研究表明,应用cfDNA游离核酸技术,可以有效、高敏感度地检测早期癌症。Apostle 艾铂图 MiniMax 游离核酸技术不断在国际上得到广泛的应用,迄今,已发表、被引用 Nature 子刊 3篇 ( Nature Medicine X 2, Nature Communications X 1), Science 子刊 1 篇, PNAS 1 篇,各种临床研究50余篇等。 祝贺此临床研究团队!期待Apostle 艾铂图技术更好地为人类做贡献。